"Burn everything nearby... including you and allies. Ignite ALL characters within 15m for 12s. Deal 5% of your maximum health/second as burning as damage. The burn is 0.5x stronger on yourself, 0.25x stronger on allies, and 24x stronger on enemies." In-game description has errors. Real radius: 15m (not 8m). Real self-damage: 2.5% max HP/s (halved by engine). Nonlethal to the holder. Lingers 3 extra seconds. Razorwire procs 5 times per second from self-damage ticks. Unlock: Multikill! - kill 15 simultaneously.
Nonlethal
Never kills self
Real Damage Numbers - In-Game Description Is Wrong
Two errors in the in-game description
1) The radius is listed as 8m but the actual radius is 15m (confirmed wrong per wiki). 2) The damage description says 5% max HP to self and 2.5% to allies, but does not account for the game engine halving all friendly-fire damage. The true numbers per second are 2.5% to self, 1.25% to allies, and 120% to enemies.
| Target |
Per Tick (5/sec) |
Per Second |
Full 12s Duration |
| Self (holder) | 0.5% max HP | 2.5% max HP/s | 30% max HP total - nonlethal |
| Allies nearby | 0.25% max HP | 1.25% max HP/s | 15% max HP total - can kill |
| Enemies | 24% max HP | 120% max HP/s | 1,440% max HP total - lethal |
Razorwire - The Core Synergy
+
5 Razorwire procs per second - automatic AoE
Hellfire Tincture hits self 5 times per second (0.5% max HP each tick)
Razorwire procs on EVERY instance of incoming damage
5 ticks/second = 5 Razorwire bursts per second firing at up to 5 targets in 25m
Each Razorwire burst deals 160% damage - with stacking this becomes massive sustained AoE
Leeching Seed on those Razorwire hits = rapid healing chain while active
Synergies and What to Avoid

RazorwireS
Procs on every self-damage tick. 5 Razorwire bursts per second hitting 25m radius automatically.
Stack Razorwire for more targets. Add Leeching Seed for healing from Razorwire hits.

PlanulaS
Heals 15 HP per incoming damage tick. 5 ticks/second = 75 HP/s from Planula alone.
Boss item from Grandparent. At 2+ stacks, Planula alone outpaces self-burn damage.

Leeching SeedA
Heals 1 HP per hit. Razorwire fires 5 times per second at 5 targets = 25 Leeching Seed hits/second.
Combine with Razorwire for passive healing loop while Tincture is active.

Repulsion Armor PlateB
Reduces each damage tick by flat 5. Five ticks/second = 25 HP saved per second.
Stacks linearly. Each plate matters since ticks are frequent and small.

Death MarkB
Helfire debuff counts toward 4-debuff threshold for Death Mark (+50% damage taken).
Invisible debuff still counts. Pair with Tri-Tip bleed and other DoTs for frequent Death Mark procs.

Ignition TankD
Converts Helfire to Stronger Burn (4x damage). Enemy damage 120% HP/s becomes 480% HP/s.
Also multiplies self-burn from 2.5% to 10% HP/s. Lethal without heavy healing.
Warning: Requires massive healing to survive. Do not pair without Planula stacks or strong regen.

Shaped GlassD
Halves max HP = halves all Tincture damage (enemy AND self). Direct nerf to this item.
Avoid entirely with Hellfire Tincture builds.
Warning: One of the few items that actively reduces Tincture's enemy damage output.
Surviving Your Own Flames
Planula is the best self-healing counter. Heals 15 HP on every damage tick. 5 Tincture ticks per second = 75 HP/s healing from Planula. At 2+ stacks you outpace self-burn entirely.
Razorwire + Leeching Seed creates a healing loop. Razorwire fires 5 times per second from self-burn ticks. Each Razorwire burst can hit multiple targets. Each hit heals via Leeching Seed. The self-burn powers the healing.
Repulsion Armor Plate reduces every tick by 5 flat damage. 5 ticks per second = 25 HP saved per second. Stack multiples for meaningful reduction.
Max HP items increase enemy damage AND survival buffer. Titanic Knurl, Infusion, and similar HP items increase both the damage Tincture deals to enemies and your total HP pool to absorb self-burn. More HP is directly better for this item.
Keep allies out of range. Allies and drones take 1.25% of your max HP per second from Tincture. In single-player this is not a concern, but multiplayer and Engineer turrets can die quickly from the sustained 15m burn aura.
Gesture + 4 Fuel Cells = permanent uptime. Base 45s CD. With sufficient CDR the Tincture re-fires before the 12s effect + 3s linger expires. Permanent 120% max HP/s enemy damage with no downtime.
Frequently Asked Questions
What does Hellfire Tincture do in Risk of Rain 2?
Hellfire Tincture is a lunar equipment that ignites all characters within 15m for 12 seconds when activated. It deals damage 5 times per second to the holder (2.5% max HP/s), allies nearby (1.25% max HP/s), and enemies (120% max HP/s). The in-game description says 8m radius and 5% self-damage - both are wrong. The radius is 15m, and all friendly-fire is halved by the game engine making the true self-damage 2.5% per second. The self-damage is nonlethal and cannot reduce the holder below 1 HP.
How do you unlock Hellfire Tincture?
Hellfire Tincture is unlocked by completing the Multikill! challenge: kill 15 enemies simultaneously in a single attack or effect. Will-o'-the-wisp, Artifact of Swarms (which halves enemy health), and explosive items that chain-kill make this achievable. Once unlocked it can appear from Lunar Pods and the Bazaar Between Time.
What does Razorwire do with Hellfire Tincture?
This is the primary reason to use Hellfire Tincture. Razorwire procs when the holder takes damage, firing blades at up to 5 targets within 25m. Hellfire Tincture ticks 5 times per second as self-damage - meaning Razorwire fires 5 times per second automatically with no combat needed. Stacking both creates a passive AoE damage machine that hits everything in 25m five times per second.
Does Shaped Glass affect Hellfire Tincture damage?
Yes, and not in a good way. Hellfire Tincture's damage is based on the holder's maximum health. Shaped Glass halves max HP, which halves the damage dealt to enemies by the Tincture. Shaped Glass is one of the few items that actively hurts the Tincture build and should be avoided.
Can Hellfire Tincture kill you?
No. The self-damage component is explicitly nonlethal - it cannot reduce the holder below 1 HP. Allies and drones caught in the radius can die, however. The Helfire debuff also lingers for 3 seconds after leaving the area or after the 12-second duration ends, during which damage continues.
How does Ignition Tank interact with Hellfire Tincture?
Ignition Tank converts the Helfire DoT to Stronger Burn, multiplying the damage 4x. This makes enemy damage go from 120% max HP/s to 480% max HP/s - devastating. However, it also amplifies the self-burn from 2.5% to 10% max HP/s. Without significant healing this will rapidly drain your HP buffer. Never use Ignition Tank with Hellfire Tincture without heavy sustain items.
Other Risk of Rain 2 Items
More Rogue Ranker Guides