Effect: +0.5 Max HP per kill, up to a maximum of 200 stacks (+100 Max HP total).
Unlock: Increase Max HP with Blood Magic 400 times (cumulative across runs)
Demonic Blood is a Rare item that permanently grows your Max HP throughout a run based on how many enemies you kill. Every kill adds +0.5 Max HP, accumulating up to a cap of 200 stacks - a total of +100 Max HP earned purely from killing enemies. The stacks are permanent within the run and do not reset between waves or stages.
On its own, +100 Max HP over the course of a run is meaningful survivability. Where Demonic Blood becomes particularly valuable is when combined with items that scale damage from Max HP - specifically Beefy Ring (+20% Damage per 100 Max HP) and Holy Book (+100 Max HP flat). Every point of Max HP that Demonic Blood adds feeds those items directly, turning kill-count survivability into kill-count damage scaling.
Some aggregate guides list Demonic Blood as "+9 Max HP with Armor/Thorns" which is inconsistent with the wiki description and observed community testing. The correct behavior per the wiki and multiple community sources is +0.5 Max HP per kill up to 200 stacks. The megabonk.org database explicitly flags the "+9 HP/Armor/Thorns" description as inaccurate. This guide uses the wiki-confirmed stacking model.
Demonic Blood sits at the beginning of a three-item HP scaling chain that the Beefy Ring wiki confirms is a core combination: Demonic Blood - Chonkplate - Beefy Ring. Here is how the chain works:
| Item | Role in the Chain | How It Interacts with Demonic Blood |
|---|---|---|
| Demonic Blood | HP generator | Adds up to +100 Max HP from kills. The source of HP for the chain. |
| Chonkplate | HP amplifier + lifesteal | Confirmed by Chonkplate wiki as a core Demonic Blood synergy. Gives +20% Lifesteal and Overheal to 75% Max HP - the higher the Max HP from Demonic Blood, the larger the Overheal ceiling. |
| Beefy Ring | HP-to-damage converter | +20% Damage per 100 Max HP. Every 100 HP Demonic Blood adds equals +20% more Damage from Beefy Ring. Also confirmed by Beefy Ring wiki as a direct synergy. |
Increase your Max HP using the Blood Magic weapon a total of 400 times. This counter is cumulative across all runs - it does not need to be done in a single run. Blood Magic gives a 5% chance per kill to permanently gain +1 Max HP, so each run with Blood Magic equipped contributes to the 400-count. After reaching 400 total Max HP gains from Blood Magic, Demonic Blood is added to your unlock shop and can be purchased with Silver.
Run Blood Magic with Size and Cooldown Tomes to maximize its AoE coverage and kill rate. Each kill has a 5% chance to trigger the HP gain, so more kills per second means faster unlock progress. Vlad starts with Blood Magic as his default weapon and the wiki specifically notes him as a key character for Blood Magic HP snowballing - making Vlad runs the most efficient path to the 400-count. Densely packed waves in later stages generate the most kill opportunities per minute.
Vlad - The wiki explicitly names Vlad as a key pick for Demonic Blood. He starts with Blood Magic as his default weapon - the same weapon required to unlock Demonic Blood - so he naturally has a head start on both the unlock grind and in-run HP accumulation. His Vampire passive gives +1% Lifesteal per level, meaning as his Max HP grows from Demonic Blood's kill stacking, each Lifesteal tick heals more HP in absolute terms. Higher Max HP from Demonic Blood also makes Chonkplate's Overheal ceiling larger and Beefy Ring's damage bonus higher, fitting directly into Vlad's sustain-heavy build identity.
Megachad - Megachad's AFK Aura playstyle generates consistent kills at a high rate throughout every wave. His high base Max HP pool means each Beefy Ring copy he holds provides more damage before Demonic Blood's stacks even begin - and as Demonic Blood adds +100 Max HP from kills, that Beefy Ring bonus grows further. Multiple AFK build guides list Beefy Ring as a core Megachad item. The Megachad character guide on megabonk.org also specifically mentions Demonic Blood alongside Beefy Ring as items for his build, making the HP-to-damage chain a natural fit for his already HP-centric playstyle.
Sir Oofie - Sir Oofie's Reinforced passive adds +1% Armor per level, making him the most naturally tank-oriented character in the game. The Chonkplate wiki page explicitly lists the Chonkplate - Demonic Blood - Beefy Ring chain as a core combination. Sir Oofie's armor investment keeps him alive long enough to accumulate the full 200 kill stacks from Demonic Blood across a run, and his naturally high survivability makes Beefy Ring's HP-to-damage conversion more reliable since he maintains high Max HP throughout rather than dropping low from chip damage.
+0.5 Max HP per kill, permanently within the run, capping at 200 stacks for a total of +100 Max HP. The bonus is cumulative through the run and does not reset between waves. Combined with Beefy Ring the extra HP converts to +20% Damage per 100 Max HP gained.
Increase your Max HP using Blood Magic a total of 400 times across any number of runs. Each kill while Blood Magic is equipped has a 5% chance to grant +1 Max HP - when your account-wide total from these procs reaches 400, Demonic Blood unlocks. Vlad starts with Blood Magic and is the most efficient character for grinding this unlock. After meeting the condition, purchase Demonic Blood from the Unlocks shop with Silver.
Yes - they are two separate items that both proc from kills simultaneously. Every kill contributes +0.5 Max HP toward Demonic Blood's 200-kill cap and +0.1% Damage toward Demonic Soul's 1,000-kill cap at the same time. Running both doubles the per-kill value of each enemy you defeat.
+100 Max HP total from a single copy - 200 kills at +0.5 Max HP each. This is on top of your base Max HP from character level, tomes, and other items. Combined with Holy Book (+100 Max HP flat), HP Tome, and Leeching Crystal (+50% Max HP), Demonic Blood is one component of reaching very high Max HP totals that significantly boost Beefy Ring's damage output.
